English: Yukon River from the Klondike Highway (Highway 2), just north of Carmacks, Yukon Territory, Canada.

The Yukon River is a major watercourse of northwestern North America. The river's source is in British Columbia, Canada, from which it flows through the Canadian Yukon Territory (itself named after the river). The lower half of the river lies in the U.S. state of Alaska. The river is 3,190 kilometres (1,980 mi) long and empties into the Bering Sea at the Yukon–Kuskokwim Delta. The average flow is 6,430 m3/s (227,000 ft3/s). The total drainage area is 832,700 km2 (321,500 mi2), of which 323,800 km2 (126,300 mi2) is in Canada. The total area is more than 25% larger than Texas or Alberta.

The longest river in Alaska and Yukon, it was one of the principal means of transportation during the 1896–1903 Klondike Gold Rush. A portion of the river in Yukon—"The Thirty Mile" section, from Lake Laberge to the Teslin River—is a national heritage river and a unit of Klondike Gold Rush International Historical Park. Paddle-wheel riverboats continued to ply the river until the 1950s, when the Klondike Highway was completed.